

You may experience the following symptoms: However, if you're using a cached mode profile, Outlook doesn't display an error. Outlook must be online or connected to complete this action. The connection to the Microsoft Exchange Server is unavailable. Check to make sure you are connected to the network and are using the proper server and mailbox name. The information store could not be opened. Unable to open your default e-mail folders.

Either there are network problems or the Microsoft Exchange Server computer is down for maintenance. The Microsoft Exchange Server computer is not available. When you start Microsoft Office Outlook by using a profile that includes a mailbox on a server that's running Microsoft Exchange Server 2010, Exchange Server 2013, or Exchange Server 2016, you may receive the following error messages:Ĭannot start Microsoft Office Outlook. The article only applies to the Microsoft Outlook connection issues that are caused by the RPC encryption requirement.
